Dihydrotestosterone’s Role in Male Sexual Function and 5?-Reductase Inhibitor Effects
Reading Time: 2 minutes Introduction to Dihydrotestosterone Dihydrotestosterone (DHT) is a potent androgen, derived from testosterone through the action of the enzyme 5?-reductase. It plays a crucial role in the development and maintenance of male sexual characteristics, including prostate growth, hair patterns, and libido. Understanding DHT's function is essential, particularly when considering therapies that target its production, such as 5?-reductase inhibitors. The Mechanism of DHT in Male Sexual Function DHT is primarily responsible for the development of male secondary sexual characteristics during puberty. It binds to androgen receptors with greater affinity than testosterone, exerting a more potent effect on target tissues. In the context...


