Secondary Hypogonadism and Podiatric Disorders in U.S. Men: Multicenter Study
Reading Time: < 1 minute Introduction Secondary hypogonadism, characterized by deficient gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus or inadequate luteinizing hormone (LH) and follicle-stimulating hormone (FSH) production by the pituitary gland, manifests as testosterone deficiency in men. Affecting approximately 2-5% of American males over 40, this endocrine disorder transcends reproductive implications, influencing musculoskeletal integrity, metabolic homeostasis, and peripheral vascular health. Recent epidemiological data from the National Health and Nutrition Examination Survey (NHANES) underscore rising prevalence amid aging demographics and lifestyle factors like obesity. Intriguingly, emerging evidence links androgen deprivation to podiatric pathologies, including plantar fasciitis, peripheral neuropathy, and osteoporotic fractures—conditions burdensome to U.S. healthcare,...


