Ipamorelin Accelerates Neurorecovery in Moderate-Severe TBI: 3-Year RCT in U.S. Males
Reading Time: 2 minutes ## Introduction Traumatic brain injury (TBI) remains a leading cause of morbidity and mortality among American males, with the Centers for Disease Control and Prevention (CDC) reporting over 2.8 million TBI-related emergency department visits annually, disproportionately affecting men aged 15-44 due to vehicular accidents, contact sports, and occupational hazards. Ipamorelin, a selective growth hormone secretagogue (GHS), mimics ghrelin to stimulate pulsatile growth hormone (GH) release via the GH-releasing hormone receptor, promoting insulin-like growth factor-1 (IGF-1) production without cortisol elevation. This three-year prospective study evaluates ipamorelin's efficacy in enhancing neurorecovery, focusing on cognitive restoration, neuroplasticity, and functional outcomes in American males...


