Sildenafil-Linked Sudden Sensorineural Hearing Loss in US Males: Case-Control Study
Reading Time: 2 minutes ## Introduction Phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil (Viagra®), have revolutionized the management of erectile dysfunction (ED) since their approval by the U.S. Food and Drug Administration (FDA) in 1998. In the United States, approximately 30 million adult males experience ED, with prevalence rising sharply among those aged 40-70 years due to comorbidities like diabetes mellitus, hypertension, and cardiovascular disease. While these agents are generally well-tolerated, post-marketing surveillance has identified rare but serious adverse events, including sudden sensorineural hearing loss (SSNHL). This retrospective audiological study examines the association between sildenafil use and auditory dysfunction in American males, drawing...


