Video Download: Researchers Ponder Why Estrogen Only Hrt May Reduce Breast Cancer Risk
Video Stream: Researchers Ponder Why Estrogen Only Hrt May Reduce Breast Cancer Risk
Breast cancer risk may decline in postmenopausal women who take estrogen-only Hormone Replacement Therapy (HRT); a review released Thursday concludes.
That represents a substantial change from how estrogen-only hormone therapy was viewed a decade ago, the authors said.
Older observational studies suggested that both of the primary forms of hormone therapy -- estrogen-only for women who have had hysterectomies and an estrogen-progestin combination for women with uteruses -- raised breast cancer risk.
The landmark Women's Health Initiative found that the estrogen-progestin combination did significantly increase the possibility of breast cancer in postmenopausal women. However, the estrogen-alone arm of the study was inconclusive.
A reanalysis of data from that study published earlier this month found that estrogen-only did not raise the risk of breast cancer and even lowered it in women who do not have risk factors for the disease, such as a family history or a history of benign breast disease.
The new review, led by Dr. Rowan T. Chlebowski of the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, again examined the Women's Health Initiative data.
They concluded that estrogen-alone significantly decreased the risk of breast cancer while estrogen-progestin significantly increased the risk.
A couple of points about hormone therapy and breast cancer are coming into focus.
One is that some of the observational studies of decades past indicating that estrogen-alone increased breast cancer may have been skewed by the fact that hormone users were also more likely to get mammograms and have their cancers detected, the authors said.
Second, it appears that breast cancer cells in postmenopausal women are highly sensitive to changes in levels of hormones and "can survive only a limited range of estrogen exposures," they said.
A substantial change in estrogen levels can halt tumor growth.
If you're a postmenopausal woman and are confused, no wonder.
As the authors state: "[C]oncepts regarding menopausal hormone therapy and breast cancer have undergone considerable change in the last decade."
Women with uncomfortable menopausal symptoms should talk to their doctors about treatment options.
Estrogen-progestin for women with uteruses will increase breast cancer risk, but women who have had hysterectomies have more choices. For everyone, Hormone Replacement Therapy involves weighing some risks and benefits.
The paper appears in the Journal of the National Cancer Institute.
Word Count: 402
Contact Us Today For A Free Consultation
- Early HRT 'May Cut Alzheimer Risk' - April 8th, 2019
- The Importance of Luteinizing Hormone - March 3rd, 2019
- A Toxic Hormone Seems to Be Changing the Sex of Fish in U.S. Rivers - February 26th, 2019
- Welcome to HGH and Testosterone Replacement Therapy - February 20th, 2019
- Doctors Call For New Guidelines as Study Finds HRT 'is Safe - and Can Protect Heart' - February 10th, 2019
- IGF-1 Treatment - February 8th, 2019
- About IGF-1 Also Known as Somatomedin C - February 8th, 2019
- Human Growth Hormone Options for Administration - February 8th, 2019
- Finally Explained: The Mysterious Pineal Gland - February 2nd, 2019
- HGH Sprays -- Fact, Fiction or Scam? - January 29th, 2019
- Gene Therapy - December 24th, 2018
- The Best Ways to Boost Your Levels of HGH - November 27th, 2018
- Human Growth Hormone Explained - November 27th, 2018
- Melatonin: The Body's Master Clock - November 27th, 2018
- Esquire: Hormone Replacement Therapy For Men: A Review - November 21st, 2018
- Behavioral Therapy May Help Hot Flashes - November 21st, 2018
- Heart Benefits From Hormone Replacement Therapy? - November 21st, 2018
- New Research on Hormone Replacement Therapy - November 21st, 2018
- Risks of Hormones in Early Menopause Challenged - November 21st, 2018
- How to Keep Your Human Growth Hormone Treatments Legal - November 19th, 2018
- Hormone Therapy May Help Cut Alzheimer's Risk - November 19th, 2018
- Androgel : Men Getting Their Mojo Back! - November 19th, 2018
- Hormone Replacement Therapy Safe, Study Suggests - November 19th, 2018
- Toxins Could Explain Pneumonia Damage While a Hormone Could be the Cure, Researchers Say - November 19th, 2018
- HGH Secretagogue - November 17th, 2018
- Injectable HGH Therapy Manual and Wiki Guide - November 17th, 2018
- The HGH Recommended Medical Dosage - The Importance of Blood Work - November 16th, 2018
- The Miracle of the Human Growth Hormone Secretagogue Sermorelin - January 30th, 2018
- What You Need to Know About the Hypothalamus Gland - January 30th, 2018