
Genetic and Environmental Factors in Secondary Hypogonadism Among American Males
Reading Time: 2 minutes Introduction Secondary hypogonadism, a condition characterized by the inadequate production of testosterone due to dysfunctions in the hypothalamus or pituitary gland, is increasingly recognized as a significant health issue among American males. This article delves into the multifaceted genetic and environmental factors that contribute to the onset and progression of this condition, offering a comprehensive analysis aimed at enhancing understanding and management strategies. Genetic Factors in Secondary Hypogonadism Genetic predispositions play a pivotal role in the development of secondary hypogonadism. Mutations in genes such as KAL1, FGFR1, and GNRHR are known to disrupt the normal function of the hypothalamic-pituitary-gonadal axis,...