
Tamoxifen’s Impact on Ovarian Function and Fertility in Breast Cancer Treatment
Reading Time: 2 minutes Introduction to Tamoxifen Tamoxifen, a selective estrogen receptor modulator (SERM), has been a cornerstone in the treatment and prevention of hormone receptor-positive breast cancer in women. Its mechanism of action involves competitively binding to estrogen receptors, thereby inhibiting the proliferative effects of estrogen in breast tissue. However, the impact of tamoxifen extends beyond its primary therapeutic target, influencing various aspects of the female reproductive system, including ovarian function. Tamoxifen's Mechanism of Action on Ovarian Function Tamoxifen's interaction with the ovaries is complex and multifaceted. While it acts as an antagonist in breast tissue, it exhibits agonist properties in other tissues,...