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Centrophenoxine (CPX) is a drug used to treat the symptoms of senile dementia and Alzheimer's disease.
It was one of the first nootropics. Developed in the 1950s, it was designed to help combat mental problems.
However, CPX has also been shown to have several additional benefits. CPX can:
Increase intelligence and improve the brain's ability to solve problems, make logical decisions and understand language
Help the brain retain long-term memory
Boost mental alertness
Improve mood and develop a positive mental outlook
Have potential life extension and anti-aging effects
Act as an antioxidant, destroying harmful free radicals and other toxins
Help remove lipofuscin (age-related metabolic cellular buildup) that may contribute to age spots.
- Unlike many supplements, one “cycle” of CPX could produce beneficial results long after the time it was taken!
CPX is a chemical compound (ester) of DMAE and provides neuroprotective capabilities. Also, it can improve the brain's memory ability.
It is a prescription drug (Lucridil) in most countries, but it is available over-the-counter in America, and easy to find online.
How Does Centrophenoxine Work?
CPX works by raising serotonin, acetylcholine, noradrenaline, and dopamine levels which support mood, mental alertness, and memory.
Centrophenoxine also has been shown to increase the supply of oxygen to the brain, which assists cognitive functioning.
It is classified as a choline source since it enhances the amount of acetylcholine mentioned above.
Acetylcholine is an important neurotransmitter that has been shown to raise intellect and can fight memory problems that are a direct result of aging.
In fact, Centrophenoxine was initially developed to help treat senility.
This is important due to this depressing statistic: over one in three people over the age of 70 experience some form of memory disorder.
The key is to prevent this nightmare from happening, and CPX should be on the front line of your prevention efforts.
As mentioned earlier, Centrophenoxine is an excellent source of choline, which is a precursor of acetylcholine, which works beneficially on some brain functions.
Increases in acetylcholine can improve synaptic plasticity, which results in an increased ability to recall memories.
CPX is a result of mixing DMAE (a natural, organic compound used to treat various central nervous system and brain disorders) with pCPA (a synthetic pesticide similar to chemicals in a group of plant hormones called auxins).
After consumption, CPX is broken down into these two precursors.
Then, the liver converts the DMAE to choline, and the remaining CPX races through the body, eventually making its way to the brain.
Here, CPX is broken down, allowing the DMAE to cross the blood-brain barrier. DMAE's partner, pCPA, has a much easier time crossing the blood-brain barrier, which means the brain gets pCPA broken down from CPX even faster.
When this combination enters the brain and goes to work, the result is some nootropic benefits.
CPX is also believed to remove potassium deposits that collect in the brain, which improves communication between the brain's neural paths.
Centrophenoxine also increases glucose activity in the brain cells, which adds still another layer of antioxidant protection to the brain.
CPX increases RNA which is used by neurons to create a protein that is used to encode memory and repair beaten-up cells in the brain.
CPX stimulates the activity of the brain by increasing the uptake of the sugar glucose, which is necessary for energy production.
Oxygen activity and carbon dioxide manufacturing also get a significant boost when CPX is taken on a regular basis.
Who Needs Centrophenoxine?
If you are having memory difficulties or feeling a bit depressed...or if you would like to prevent these conditions from affecting you...then CPX is a supplement that you should consider.
Interestingly, athletes in training have reported that centrophenoxine helps them increase their strength and recover quicker from grueling workouts.
This is thought to occur because CPX increases oxygen input due to improved cardiovascular capabilities, which increases oxygen supply to the brain.
Finally, Centrophenoxine has helped lessen the appearance of age spots in elderly people.
Centrophenoxine is considered safe, is usually well-tolerated, and has no known toxicity or drug interaction levels.
There have been a few side effects reported: upset stomach, mild dizziness, irritability, headaches, and insomnia.
While rare, be aware of these possibilities and either discontinue use or lower the dosage.
Taking CPX every other day has solved this problem for some folks.
People with high blood pressure or specific convulsive disorders such as epilepsy, as well as pregnant women should avoid using CPX.
CPX works well with other nootropics and smart drugs like the racetam family.
If used in combination with other cognitive enhancers, the effects are synergistic (resulting in a more significant impact than if all the substances were taken individually). However, users are advised to discuss this with a doctor or other healthcare professional to be on the safe side.
Food sources of choline are egg yolks and beef liver. However, most people do not get anywhere near the recommended amount of choline in their diet to be helpful. Therefore, supplementing is highly recommended.
The recommended CPX dosage is in the 250-500 mg daily, taken in two 250 mg doses, one in the morning and one in the afternoon. Centrophenoxine is water-soluble, so it is recommended to take it with food.
As with other nootropics, due to many variables, it's hard to predict precisely how effective CPX will work for a particular person.
The bottom line is this: Centrophenoxine is one of the rare supplements that has something to offer almost everyone!
From memory improvement to stress reduction, improved mood, and even better athletic performance, CPX holds out the promise to do all of these things.
This inexpensive and easy-to-obtain supplement is something you should consider adding to your supplement program.
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