Dr. Paresh Dandona and colleagues from the State University of New York in Buffalo measured circulating Testosterone levels in 38 men with type 1 diabetes and 24 men with type 2 diabetes.
Results showed that Testosterone levels were significantly lower in participants with type 2 diabetes than they were in men with type 1 diabetes. 33% of participants with type 2 diabetes were found to have low Testosterone levels, while 58% had Testosterone levels that were below normal for their age.
In comparison, just 8% type 1 diabetic patients had Testosterone levels below the lower limit of normal.
The participants with low Testosterone also had low levels of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), thus meaning that they met diagnostic criteria for hypogonadotropic hypogonadism, by not producing those two hormones in adequate amounts.
If left untreated, hypogonadotropic hypogonadism may lead to the development of osteoporosis and cardiovascular disease, as well as loss of sex drive, impotence and infertility.
The researchers conclude: “Young type 2 diabetic patients have significantly lower plasma concentrations of total and free testosterone and inappropriately low LH and FSH concentrations with a very high prevalence of hypogonadotropic hypogonadism when compared with type 1 diabetic patients of a comparable age.
The potential implications for their sexual and reproductive function during prime reproductive years are profound.”
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